Expert Pathology and Histology: Foundation for Preclinical Advancement
Our commitment to preclinical research excellence underpins our comprehensive pathology services and specialized histology services. We empower medical and biotechnology innovation by delivering the critical insights and high-quality data your programs demand.
Commitment to Excellence
At Veranex, our pursuit of excellence defines our client-centric pathology services. These feature expert macroscopic evaluations and meticulous histology services, including detailed slide analysis. We are committed to delivering your results promptly and cost-effectively.
Innovative Pathology Services at Veranex

Comprehensive Pathology
We offer an integrated, comprehensive, state-of-the-art, and GLP-compliant portfolio of services that includes:
- Sample processing
- Evaluation
- Interpretation
- Reporting
These services are essential for assessing the safety, performance, and efficacy of new biomaterials or devices.

The Role of Pathology
Pathology plays a crucial role in the evaluation of device safety and performance in preclinical research and represents a gold-standard in GLP studies. It holds a central position in regulatory guidance documents such as:
- ISO 10993
- ASTM International
- EMEA guidelines
- FDA recommendations
Through meticulous macroscopic and microscopic evaluations performed on carefully selected large models, we provide critical information regarding biological responses to medical devices or biomaterials.

Detailed Protocol Design
Our protocol design, macroscopic assessment, and tissue sampling are performed by pathology professionals in close collaboration with surgeons. Histopathological observations are evaluated in the context of:
- Clinical outcomes
- Imaging data
- Macroscopic findings at the time of explanation
This ensures comprehensive and integrated interpretations.

Experienced Pathology Staff
Unlock Advanced Insights with Expert Pathology. Our experienced team delivers responsive pathology services tailored to your needs. While mastering routine histology services (paraffin, special stains, IHC), Veranex uniquely offers advanced plastic embedding for challenging medical devices and hard tissues.
Our Mission
The mission of Veranex is to provide the highest quality histology and pathology services to successfully accommodate the wide-ranging needs of our research, preclinical, and clinical clients across academic, governmental, industrial, and medical fields. The knowledgeable and professional staff of Veranex have a proven history of working diligently with our clients to accomplish their goals through both industry-proven and innovative methodologies.
Experience the excellence and reliability of Veranex Pathology Services, where science and innovation meet to advance preclinical research.




State of the Art Pathology Facilities at Veranex
Our labs are designed to meet all the equipment needs, ensuring that our clients have access to the best tools for their projects. Both our Paris and Worcester facilities work seamlessly together, this integrated approach mobilizes our extensive experience and promotes collaboration, ultimately benefiting our clients with more speed and flexibility in their projects.
Paris Lab
Our Paris lab offers a comprehensive suite of pathology services, including macroscopic evaluation, sample processing, and histopathological evaluation.
These services are essential for assessing the safety and performance of new biomaterials and medical devices. The Paris facility is GLP-compliant (FDA & OECD) and plays a crucial role in regulatory guidance documents such as ISO 10993, ASTM International, EMEA guidelines, and FDA recommendations.
The team in Paris includes 3 skillfull and experienced technicians, who perform necropsies and tissue samplings and prepare resin sections.
Two certified veterinary pathologists (Dr. Laurence Fiette and Dr. Gauthier Terrade work in the facility of Paris.

Worcester Lab
Our Worcester, Massachusetts lab is renowned for its industry-leading histopathology protocols, developed and implemented by Dr. James Stanley.
With over two decades of experience, the Worcester team brings unparalleled expertise to the table, benefiting a broad range of investigators and researchers in preclinical, academic, and governmental fields.
The team in Worcester includes, Kate San Souci, Director, Research Pathology, who is responsible for the global oversight of the facility’s full-service histopathology products and compliance programs.
James Stanley is leading the Worcester lab as veterinary pathologist.

Best-In-Class Equipment
Both our Paris and Worcester facilities are equipped with the best and most advanced equipment available in the industry.
Our labs are designed to meet all the equipment needs essential for comprehensive research, ensuring that our clients have access to the best tools for their projects.
Comprehensive Histopathological and Specialized Services
At Veranex, we offer a wide range of histopathological techniques and specialized services to meet the diverse needs of our clients in research, preclinical, and clinical fields. Our services are designed to provide high-quality, reliable results that support the safety, performance, and efficacy assessments of new biomaterials and devices.
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Histopathological Techniques
- Tissue Trimming: Trimming of tissues and organs.
- Decalcification: Specific protocols for effective decalcification of tissues.
- Frozen Sections: Provision of frozen sections using a cryostat and experienced staff.
- Custom Staining: Protocols, dyes, and solutions for routine and special staining techniques.
- IHC and IF Staining: Optimization and validation of immunohistochemical and immunofluorescent staining.
- Traveling Necropsy: Off-site prosection services for medical devices, biopharmaceuticals, and biologic therapies.
- Paraffin Embedding & Sectioning: Standard paraffin processing, embedding, and microtomy.
- Histochemical Staining: A wide range of routine and special histochemical stains.
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Specialized Services
- Immunohistochemistry: Development and application of routine and novel immunohistochemical markers.
- Slide Imaging/Scanning: High magnification slide scanner for online viewing and file delivery.
- Necropsy Services: Supervised necropsies and macroscopic evaluations by certified veterinary pathologists.
- General Histology Services: Routine histology including paraffin embedding, sectioning, and special stains.
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Specialized Tissue Processing
- PMMA and Spurr Resin Embedding: For evaluation of large or hard implants in undecalcified tissues.
- EXAKT® Cutting and Grinding: Techniques for precise tissue analysis.
- Whole Slide Imaging: Digitalization of histological slides for archiving and telepathology.
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Histopathological Evaluation
- Morphometry: Quantitative measurement of histological parameters using professional software.
- Pathology Reporting: Comprehensive, illustrated reports including narrative descriptions and quantitative assessments.
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Additional Offerings
- Microphotographing: Remarkable microphotographs for regulatory purposes, illustration of histological observations and publication.
- Customized Measurements: Tailored evaluations to meet specific study needs.
- Oral Presentations: Scientific discussions and presentations with study pathologists upon request.
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General Histology Services
We offer the following routine histology services:
- Paraffin embedding and sectioning
- Routine HE&S staining
- Frozen Sectioning
- Special Stains
Applications
- Cusps from prosthetic valves
- Soft devices or biomaterials (vascular conduits, artificial ureters, bladder, surgical sealants, patches, etc.)
- Target/distant organs (kidney, liver, lung, or brain) for the assessment of systemic effects
Special stains are very useful in the qualitative assessment of histological sections and complement HE&S as they specifically stain some components of normal or pathological tissues. We developed routine panels of special stains for cusps of prosthetic valves, cartilage, biomaterials, or other tissues.
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Immunohistochemistry
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Specific immunolabelling is a valuable ancillary method to visualize and quantify cells or tissue components. We perform immunohistochemistry for endothelial cells, collagen fibers, smooth muscle cells, myofibroblasts, or inflammatory cell populations and sub-populations, and can also develop personalized protocols to fit your needs and endpoints.
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Specialized Tissue-Implants Processing
- PMMA and Spurr Resin Embedding
- EXAKT® Cutting and Grinding
- H&E and Masson Trichrome Staining of Resin Sections
This highly-specialized technique is typically used for the evaluation of large and/or hard implants or soft/hard implants in undecalcified tissues. It allows maintaining tissue-implant integrity, enabling accurate evaluation of the intimate interface between the biomaterial and implanted tissues.
Applications
- Heart valves
- Metallic stents
- Orthopedic implants
- Artificial cartilage
- Ophthalmic implants
- etc.
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Whole Slide Imaging
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We can take over the digitalization of histological slides for permanent archiving, telepathology, or quantitative measurements.
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Histopathological Evaluation
The microscopic evaluation of your study will be performed by certified, experienced veterinary pathologists. The study pathologist will qualitatively describe and interpret the microscopic findings with regard to the study endpoints, using international histological guidelines. A semi-quantitative score of severity with predetermined criteria will be applied. These criteria are defined to meet the specific aims of your study. The pathologist will also take remarkable microphotographs of representative findings from the study that are suitable for regulatory purposes and for publishing.
Histopathological evaluations are conducted according to internal standard operating procedures and to current highest professional and scientific standards in the spirit of ISO10993-Part 6: Tests for Local Effects after Implantation and ISO10993-Part 11: Test for Systemic toxicity. All evaluations can be conducted in compliance with Good Laboratory Practice (GLP) and audited by the Quality Insurance Unit of Veranex.
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Morphometry
Quantitative parameters (fibrous pannus thickness, remnants of the implanted biodegradable material, bone-implant contact, or vessel stenosis, etc.) can be measured on histological sections with professional software. We use dedicated protocols for the histomorphometric evaluation of heart valves, stents, bone reconstruction, and dental implants. Customized measurements can also be applied to fit your specific needs.
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Pathology Reporting
Our hallmark is clear, didactic, and richly illustrated reports with annotated pictures.
The histopathology report includes:
- Narrative description of microscopic changes and interpretation
- Qualitative and semi-quantitative assessment of microscopic changes
- Individual data
- Representative microphotographs Histomorphometry data
In addition:
- The images can be professionally edited for publication-ready submission
- An oral presentation of the pathological data and scientific discussion with the study pathologist and other members of the scientific staff can be organized upon request
Experience the excellence and reliability of Veranex Pathology Services, where science and innovation meet to advance preclinical research.
Meet the Team
Your Pathology Services Experts
Get to know the specialists whose passion and knowledge deliver the clarity and strategic foresight your needs for success.
Laurence Fiette
DVM, DESAPV, PhD, HDR
Dr. Fiette completed her training in veterinary medicine, Board certification in Veterinary Pathology (DES) and PhD in virology at prestigious institutions in France. PShe worked in academic research at the Institut Pasteur in Paris as an Experimental Pathologist ion animal models of human infectious diseases and cancer and authored and co-authored more than 80 research articles and book chapters. She also worked as a consultant for IMMR and joined IMMR as Head of the Pathology Department prior to the acquisition of IMMR by Veranex. . Dr Fiette has many years of experience in pathology of medical devices. She is also active in teaching and organizing international scientific meetings in the fields of animal models and pathology. She is now Senior Director, Research pathology at Veranex PCS, Paris, France.
Gauthier Terrade
DVM, MSc, DESV-APV
Dr. Terrade completed his veterinary degree and Board certification in Veterinary Pathology (DESV) at leading institutions in France. He also earned a Master’s degree in virology from the Institut Pasteur in Paris. During his veterinary training, he developed a strong interest in academic research, pathophysiology, and comparative medicine. He completed internships in renowned academic laboratories in France and at the University of California, Davis, after being awarded a place in the Boehringer Ingelheim Veterinary Scholars Program, a competitive research initiative for veterinary students. Dr. Terrade joined IMMR in 2021, prior to the acquisition of IMMR by Veranex, as a part-time pathology trainee early in his specialization. He transitioned to a full-time position as Research Pathologist at Veranex PCS, Paris, following his certification in 2024. He is the author and co-author of several research articles on animal models of human disease and the histopathological evaluation of medical devices.
Dr. James ‘Butch’ Stanley
DVM, MS, DACVP
As the Scientific Director and Boarded Veterinary Pathologist at Veranex, Dr. Stanley brings nearly two decades of experience in assisting a wide range of investigators and researchers in preclinical, academic, and governmental fields with the development and implementation of the histopathology protocols necessary to successfully meet their project goals. Dr. Stanley has developed an expertise in the safety and/or efficacy assessment of biomaterials, medical devices, surgical and disease models, and pharmaceuticals related to biomaterials, devices, and therapeutics in numerous anatomic locations including cardiovascular, bone, dermal, gastrointestinal, and neurological. In addition, as the Director of Pathology in several preclinical CRO’s, Dr. Stanley has developed the novel approaches and protocols required for the prosection and removal of novel biomaterials and devices in multiple species.
Kate San Souci
HT (ASCP)
As Veranex’s, Director, Research Pathology, Kate is responsible for the global oversight of the facility’s full-service histopathology products and compliance programs. She began her career in early 2006 where she was trained on-the-job at a Boston area contract research organization. From there, the art of histology became her hobby and trade. Kate was ASCP certified in 2010 and has participated in a variety of industries (CROs, Hospitals, Veterinary Diagnostic, Contract Necropsy). Over the past 14 years, she has developed expertise in paraffin, frozen, and plastic histology methods, as well as immunohistochemistry. She is also well trained in post-mortem examination and tissue collection on most species, the vast majority including delicate prosection of medical devices/implants. Over the years, Kate also developed a talent for personnel and program management and is thrilled to be in a leadership position that allows for technical, hands-on histology satisfying her interest in the art.
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Transform Your Research with Veranex Pathology Services
Unlock the full potential of your with Veranex's state-of-the-art pathology services. Contact us today to discover how our cutting-edge labs and expert team can elevate your projects.



